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Begins with an historical overview of the early discoveries surrounding DNA methylation in the mammalian brain and then explores the evidence supporting a role for this epigenetic mechanism in controlling gene expression programs across the lifespan in both normal and diseased states. Chapters describe new directions and technological advances, and provide an overview of what the future holds for this exciting new field. This book is ideal for medical, graduate and advanced undergraduate students, but is also a great resource for researchers who need a broad introduction to the dynamic nature of DNA that sheds light on evolving concepts of gene-environment interaction and their effects on adaptation and neuropsychiatric disease.--
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Begins with an historical overview of the early discoveries surrounding DNA methylation in the mammalian brain and then explores the evidence supporting a role for this epigenetic mechanism in controlling gene expression programs across the lifespan in both normal and diseased states. Chapters describe new directions and technological advances, and provide an overview of what the future holds for this exciting new field. This book is ideal for medical, graduate and advanced undergraduate students, but is also a great resource for researchers who need a broad introduction to the dynamic nature of DNA that sheds light on evolving concepts of gene-environment interaction and their effects on adaptation and neuropsychiatric disease.--
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Gene expression --- Gene expression. --- Cytology --- Gene expression regulation --- Genes --- Congresses.
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evolution. --- evolution --- gene expression --- gene expression
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Gene expression. --- Genetic regulation. --- Gene expression regulation.
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This book, first published in 1996, is a concise yet fully informative coverage of the structure and function of genes. It describes DNA and how it replicates, how DNA is transcribed and translated into proteins, the organisation of genes in prokaryotes and eukaryotes, the control of gene expression and the role of retroviruses and oncogenes in cancer. There are additional discussions of gene families, genes and the immune systems and mitochondrial and chloroplast genomes. This is a third edition of a successful undergraduate text. It has been extensively updated, particularly in regard to advances in our understanding of replication and transcription.
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